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1

Teratogenic effects of cholinergic insecticides in chick embryos I. Diazinon treatment on acetylcholinesterase and choline acetyltransferase activities

Miwa Misawa, John Doull, Paul A. Kitos, Edwin M. Uyeki

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 838 KB

english, 1981

2

Factors affecting the production of glutamine in cultured mouse cells

Paul R. Barnes, Dean Youngberg, Paul A. Kitos

Journal:

Journal of Cellular Physiology

Year:

1971

Language:

english

File:

PDF, 808 KB

english, 1971

3

Multisubstrate analogue based on 5,8,10-trideazafolate

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren, Joseph Ramcharan, Paul A. Kitos, Stephen J. Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 417 KB

english, 1997

4

Streptonigrin and lavendamycin partial structures. Probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones

Boger, Dale L., Yasuda, Masami, Mitscher, Lester A., Drake, Steven D., Kitos, Paul A., Thompson, Sandra Collins

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1.58 MB

english, 1987

5

The metabolism of L-glutamate and L-5-Carboxypyrrolidone by mouse cells (NCTC clone 929) under conditions of defined nutrition

Paul A. Kitos, Charity Waymouth

Journal:

Journal of Cellular Physiology

Year:

1966

Language:

english

File:

PDF, 1.25 MB

english, 1966

6

Purine uptake by azaguanine-resistant chinese hamster cells

Marilyn Parsons, Dr. John Morrow, Douglas Stocco, Paul Kitos

Journal:

Journal of Cellular Physiology

Year:

1976

Language:

english

File:

PDF, 654 KB

english, 1976

7

Pentose phosphate pathway activity of the chick embryo in ovo

Eleanor Wenger, Byron S. Wenger, Paul A. Kitos

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1967

Language:

english

File:

PDF, 761 KB

english, 1967

8

Identification of Serine Esterases in Tissue Homogenates

Ali Keshavarz-Shokri, Oranart Suntornwat, Paul A. Kitos

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

9

A Hammett correlation for CC-1065 and duocarmycin analogs: Magnitude of substituent electronic effects on functional reactivity

Dale L. Boger, Jeffrey A. McKie, Nianhe Han, Christine M. Tarby, Haiqiong W. Riggs, Paul A. Kitos

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 289 KB

english, 1996

10

Key analogs of the tetrapeptide subunit of RA-VII and deoxybouvardin

Dale L. Boger, Jiacheng Zhou, Brian Winter, Paul A. Kitos

Journal:

Bioorganic & Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.39 MB

english, 1995

11

Synthesis and preliminary evaluation of (+)-CBI-indole2: an enhanced functional analog of (+)-CC-1065

Dale L. Boger, Takayoshi Ishizaki, Subas M. Sakya, Stephen A. Munk, Paul A. Kitos, Qing Jin, Jeffrey M. Besterman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 423 KB

english, 1991

12

DNA alkylation properties of the duocarmycins: (+)-duocarmycin A, epi-(+)-duocarmycin A, ent-(−)-duocarmycin A and epi,ent-(−)-duocarmycin A

Dale L. Boger, Weiya Yun, Shiro Terashima, Yasumichi Fukuda, Kazuhiko Nakatani, Paul A. Kitos, Qing Jin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 3.50 MB

english, 1992

13

Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs

Dale L. Boger, Michael A. Patane, Qing Jin, Paul A. Kitos

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.93 MB

english, 1994

14

Functionalized analogues of 5,8,10-trideazafolate: Development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren, Joseph Ramcharan, Paul A. Kitos, Stephen J. Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 695 KB

english, 1997

15

Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): An effective inhibitor of glycinamide ribonucleotide transformylase

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren, Joseph Ramcharan, Ariane E. Marolewski, Paul A. Kitos, Stephen J. Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 564 KB

english, 1997

16

Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren, Lata T. Gooljarsingh, Joseph Ramcharan, Paul A. Kitos, Stephen J. Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 759 KB

english, 1997

17

Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors

Dale L Boger, Monica J Kochanny, Hui Cai, Diane Wyatt, Paul A Kitos, M.S Warren, J Ramcharan, Lata T Gooljarsingh, Stephen J Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 415 KB

english, 1998

18

Estimating the number of viable animal cells in multiwell culture—a tetrazolium-based assay

Gale Haslam, Mark Richter, Diane Wyatt, Qi-Zhuang Ye, Paul Kitos

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

19

Evaluation of bouvardin, deoxybouvardin, and RA-I - RA-VII partial structures: reassignment of the pharmacophore

Dale L. Boger, James B. Myers, Daniel Yohannes, Paul A. Kitos, Oranart Suntomwat, John C. Kitos

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 216 KB

english, 1991

20

A potent, simple derivative of an analog of the CC-1065 alkylation subunit

Dale L. Boger, Takayoshi Ishizaki, Hamideh Zarrinmayeh, Paul A. Kitos, Oranart Suntornwat

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 308 KB

english, 1991

21

Evaluation of functional Analogs of CC-1065 and the Duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (C2BI) alkylation subunit

Dale L. Boger, Douglas S. Johnson, Moorthy S.S. Palanki, Paul A. Kitos, Jiyoung Chang, Paul Dowell

Journal:

Bioorganic & Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.18 MB

english, 1993

22

10-formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): A potent inhibitor of glycinamide ribonucleotide transformylase

Dale L. Boger, Nancy-Ellen Haynes, Paul A. Kitos, Mark S. Warren, Joseph Ramcharan, Ariane E. Marolewski, Stephen J. Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.29 MB

english, 1997

23

Estimating the number of viable animal cells in multi-well cultures based on their lactate dehydrogenase activities

Gale Haslam, Diane Wyatt, Paul A. Kitos

Journal:

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

24

Do organophosphate insecticides inhibit the conversion of tryptophan to NAD+ in ovo?

Melodie Henderson, Paul A. Kitos

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1982

Language:

english

File:

PDF, 738 KB

english, 1982

25

Regulation of glutamine synthetase in L cells by cortisol andl-glutamine

Paul R. Barnes, Robert T. Hersh, Paul A. Kitos

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1974

Language:

english

File:

PDF, 780 KB

english, 1974

26

Perceiving mitosis in eukaryotic cells

Hae-Young Kim, Dennis Byrne, Paul Hwang, Sandra Collins Thompson, Paul A. Kitos

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1988

Language:

english

File:

PDF, 2.08 MB

english, 1988

27

A demonstration of the intrinsic importance of stabilizing hydrophobic binding and non-convalent van der waals contacts dominant in the non-covalent CC-1065/B-DNA binding

Dale L. Boger, Benedict J. Invergo, Robert S. Coleman, Hamideh Zarrinmayeh, Paul A. Kitos, Sandra Collins Thompson, Terence Leong, Larry W. McLaughlin

Journal:

Chemico-Biological Interactions

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

28

Precision delivery of small volumes of liquids to very young avian embryos: II. Description of the injection system

Paul A. Kitos, Charles R. Wyttenbach, Kenneth Olson, Edwin M. Uyeki

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 348 KB

english, 1981

29

Precision delivery of small volumes of liquids to very young avian embryos: I. Locating and positioning the embryo in ovo

Charles R. Wyttenbach, Sandra Collins Thompson, James C. Garrison, Paul A. Kitos

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 716 KB

english, 1981

30

Effects of molecular oxygen on chick limb bud chondrogenesis

Paul M. Hwang, Dennis H. Byrne, Paul A. Kitos

Journal:

Differentiation

Year:

1988

Language:

english

File:

PDF, 842 KB

english, 1988

31

Teratogenic effects of cholinergic insecticides in chick embryos—II: Effects on the NAD content of early embryos

Paul A. Kitos, Douglas S. Anderson, Edwin M. Uyeki, Miwa Misawa, Charles R. Wyttenbach

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 2.54 MB

english, 1981

32

Teratogenic effects of cholinergic insecticides in chick embryos—IV: The role of tryptophan in protecting against limb deformities

Dennis H. Byrne, Paul A. Kitos

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 1.09 MB

english, 1983

33

Effects of diazinon on nucleotide and amino acid contents of chick embryos: Teratogenic considerations

Sem Kushaba-Rugaaju, Paul A. Kitos

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 800 KB

english, 1985

34

The effects of dexamethasone on histone phosphorylation in L cells

David A. Prentice, Sarah E. Taylor, Newmark Z. Marjorie, Paul A. Kitos

Journal:

Biochemical and Biophysical Research Communications

Year:

1978

Language:

english

File:

PDF, 469 KB

english, 1978

35

Synthesis, Chemical Properties, and Preliminary Evaluation of Substituted CBI Analogs of CC-1065 and the Duocarmycins Incorporating the 7-Cyano-1,2,9,9a-tetrahydrocyclopropa[ c ]benz[ e ]indol-4-one Alkylation Subunit: Hammett Quantitation of the Magnitude of Electronic Effects on Functional Reactivity

Boger, Dale L., Han, Nianhe, Tarby, Christine M., Boyce, Christopher W., Cai, Hui, Jin, Qing, Kitos, Paul A.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 888 KB

english, 1996

36

Evidence for more than one mechanism of action of the glucocorticoid hormones

Keller, Bradley T., Landes, Gregory M., Kitos, Paul A.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1982

Language:

english

File:

PDF, 894 KB

english, 1982

37

Perceiving Mitosis in Eukaryotic Cells

Hae-Young Kim, Dennis Byrne, Paul Hwang, Sandra Collins Thompson and Paul A. Kitos

Journal:

In Vitro Cellular & Developmental Biology

Year:

1988

Language:

english

File:

PDF, 1.16 MB

english, 1988

38

Duocarmycin-pyrindamycin DNA alkylation properties and identification, synthesis, and evaluation of agents incorporating the pharmacophore of the duocarmycin-pyrindamycin alkylation subunit. Identification of the CC-1065 duocarmycin common pharmacophore

Boger, Dale L., Ishizaki, Takayoshi, Zarrinmayeh, Hamideh, Munk, Stephen A., Kitos, Paul A., Suntornwat, Oranart

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 3.23 MB

english, 1990

39

Histone H2A phosphorylation in animal cells: functional considerations

Prentice, David A., Loechel, Steven C., Kitos, Paul A.

Journal:

Year:

1982

Language:

english

File:

PDF, 2.91 MB

english, 1982

40

Total synthesis and evaluation of (.+-.)-N-(tert-butoxycarbonyl)-CBI, (.+-.)-CBI-CDPI1, and (.+-.)-CBI-CDPI2: CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocyclopropa[1,2-c]benz[1,2-e]indol-4-one (CBI) left-hand subunit

Boger, Dale L., Ishizaki, Takayoshi, Wysocki, Ronald J., Munk, Stephen A., Kitos, Paul A., Suntornwat, Oranart

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 416 KB

english, 1989

41

Synthesis of N-(tert-butyloxycarbonyl)-CBI, CBI, CBI-CDPI1, and CBI-CDPI2: enhanced functional analogs of CC-1065 incorporating the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) left-hand subunit

Boger, Dale L., Ishizaki, Takayoshi, Kitos, Paul A., Suntornwat, Oranart

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.30 MB

english, 1990

42

Reversed and Sandwiched Analogs of Duocarmycin SA: Establishment of the Origin of the Sequence-Selective Alkylation of DNA and New Insights into the Source of Catalysis

Boger, Dale L., Bollinger, Bernd, Hertzog, Donald L., Johnson, Douglas S., Cai, Hui, Mésini, Philippe, Garbaccio, Robert M., Jin, Qing, Kitos, Paul A.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 530 KB

english, 1997

43

Synthesis and evaluation of aborted and extended CC-1065 functional analogs: (+)- and (-)-CPI-PDE-I1, (+)- and (-)-CPI-CDPI1, and (.+-.)-, (+)-, and (-)-CPI-CDPI3. Preparation of key partial structures and definition of an additional functional role of the CC-1065 central and right-hand subunits

Boger, Dale L., Coleman, Robert S., Invergo, Benedict J., Sakya, Subas M., Ishizaki, Takayoshi, Munk, Stephen A., Zarrinmayeh, Hamideh, Kitos, Paul A., Thompson, Sandra Collins

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 3.53 MB

english, 1990

44

Synthesis of N-(tert-butyloxycarbonyl)-CBI, CBI, CBI-CDPI1, and CBI-CDPI2: enhanced functional analogs of CC-1065 incorporating the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) left-hand subunit [Erratum to document cited in CA113(23):211667n]

Boger, Dale L., Ishizaki, Takayoshi, Kitos, Paul A., Suntornwat, Oranart

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 167 KB

english, 1991

45

Antimicrobial and antitumor properties of 9,10-dihydrophenanthrenes: structure activity studies on juncusol

Boger, Dale L., Mitscher, Lester A., Mullican, Michael D., Drake, Steven D., Kitos, Paul

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 653 KB

english, 1985

46

Total synthesis and preliminary evaluation of (+)- and ent-(-)-duocarmycin SA

Boger, Dale L., Machiya, Kozo, Hertzog, Donald L., Kitos, Paul A., Holmes, Daniel

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 1.52 MB

english, 1993

47

Adsorption of polyadenylate and other polynucleotides to unmodified cellulose

Kitos, Paul A., Amos, Harold

Journal:

Year:

1973

Language:

english

File:

PDF, 717 KB

english, 1973

48

Demonstration of a Pronounced Effect of Noncovalent Binding Selectivity on the (+)-CC-1065 DNA Alkylation and Identification of the Pharmacophore of the Alkylation Subunit

Dale L. Boger, Hamideh Zarrinmayeh, Stephen A. Munk, Paul A. Kitos and O. Suntornwat

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.11 MB

english, 1991

49

Regulation of Glutamine Synthetase in L Cells by Cortisol and L-Glutamine

Paul R. Barnes, Robert T. Hersh and Paul A. Kitos

Journal:

Year:

1974

Language:

english

File:

PDF, 509 KB

english, 1974

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